All of the following are true regarding penicillin G except:-
Correct Answer: Probenecid decreases it duration of action
Description: Probenecid inhibits tubular secretion and increase the duration of action of penicillin G Penicillin G is sho acting. To overcome this problem: Benzathine and procaine group can be added to penicillin G to make it long acting. Benzathine penicillin G is longest acting penicillin. Probenecid can be administered with penicillins. Former inhibits the tubular secretion. Penicillins have wide therapeutic index. A high initial dose can be used.
Category:
Pharmacology
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