**Core Concept**
G-6PD (Glucose-6-phosphate dehydrogenase) deficiency is an X-linked recessive disorder characterized by a deficiency of the enzyme glucose-6-phosphate dehydrogenase, which is crucial for maintaining the integrity of red blood cells. This enzyme is essential for the pentose phosphate pathway, protecting red blood cells from oxidative stress.

**Why the Correct Answer is Right**
The correct answer is one of the options provided below. The correct answer will be the option that does not accurately describe G-6PD deficiency.

**Why Each Wrong Option is Incorrect**
**Option A:** G-6PD deficiency is caused by a deficiency of the enzyme glucose-6-phosphate dehydrogenase. This statement is true.
**Option B:** G-6PD deficiency is more common in males than females due to its X-linked recessive inheritance pattern. This statement is true.
**Option C:** Common precipitating factors for acute hemolysis in G-6PD deficiency include infection, certain medications, and exposure to fava beans. This statement is true.
**Option D:** G-6PD deficiency is associated with an increased risk of thrombotic thrombocytopenic purpura (TTP). This statement is false.

**Clinical Pearl / High-Yield Fact**
A classic exam trap to remember is that fava beans are a common precipitating factor for acute hemolysis in G-6PD deficiency, and patients should be advised to avoid them.

**Correct Answer:** D. G-6PD deficiency is associated with an increased risk of thrombotic thrombocytopenic purpura (TTP).