Biochemistry All of the following are true about Sickle cell disease, except A Single nucleotide change results in change of Glutamine to valine B RFLP results from a single base change C 'Sticky patch' is generated as a result of replacement of a non polar residue with a polar residue D HbS confers resistance against malaria in hetrozygotes π‘ Explanation All of the following are true about Sickle cell disease, except β Correct Answer: C. 'Sticky patch' is generated as a result of replacement of a non polar residue with a polar residue