All of the following are true about pyruvate dehydrogenase deficiency, EXCEPT
Correct Answer: Decrease in blood lactate
Description: PDH complex deficiency results in : Rise in pyruvate Upregulating other reactions of pyruvate metabolism (reduction to lactate by NADH-requiring LDH leading to lactic acidosis.) The most common form of PDH complex deficiency is caused by mutations to E1.
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Biochemistry
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