All of the following are true about Methicillin Resistance in MRSA, EXCEPT:
Correct Answer: Resistance is primarily mediated /transmitted plasmids
Description: Multi drug-resistant Staphylococcus aureus (MRSA) becomes resistant to Methicillin due to the alteration in the Penicillin Binding Proteins (PBP-2A) which carries out the functions of PBP's which are inactivated by Methcillin. This is transmitted the MeC A gene. Which is a chromosomal gene (and not a plasmid). Borderline resistance to methicillin may be produced due to hyper production of Beta Lactamases and low resistance to MRSA (hetero resistance) may be missed at 37degC and temperature of incubation no higher than 35degC is recommended but however these are not the primary cause. Ref: Methicillin-Resistant Staphylococcus Aureus (MRSA) Protocols By Yinduo Ji, Volume 391; Lippincott's Illustrated Reviews: Pharmacology, 4th Edition, Page 326
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now