Pharmacology All of the following are true about HMG CoA reductase inhibitors except: A CNS accumulation of simvastatin and lovastatin is high and less for pravastatin and fluvastatin B Simvastatin is rapidly and pravastatin is least metabolized. C Bioavailability is minimally modified when pravastatin is taken with food D Fibrinogen levels are increased by pravastatin 💡 Explanation All of the following are true about HMG CoA reductase inhibitors except: ✓ Correct Answer: D. Fibrinogen levels are increased by pravastatin