All of the following are true about bullous impetigo EXCEPT –
**Core Concept**
Bullous impetigo is a type of skin infection caused by Staphylococcus aureus, characterized by the formation of large blisters or bullae. This condition is often associated with the production of exfoliative toxins by the bacteria, leading to epidermal cleavage and blister formation.
**Why the Correct Answer is Right**
Bullous impetigo is indeed caused by Staphylococcus aureus, and the production of exfoliative toxins is a key factor in the development of this condition. These toxins cleave the desmoglein 1 protein, leading to the formation of large blisters. Bullous impetigo typically affects the face and extremities, and can be treated with antibiotics such as mupirocin.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because bullous impetigo is not typically associated with group A beta-hemolytic streptococci (GABHS).
* **Option B:** This option is incorrect because bullous impetigo is not characterized by the presence of eosinophils in the blister fluid.
* **Option C:** This option is incorrect because bullous impetigo is not typically treated with topical corticosteroids, as this can exacerbate the infection.
**Clinical Pearl / High-Yield Fact**
Bullous impetigo should be distinguished from other blistering conditions, such as pemphigus vulgaris, which is an autoimmune disease that also involves the cleavage of desmoglein 1 protein. However, pemphigus vulgaris is typically associated with a more widespread distribution and a higher risk of complications.
**Correct Answer: A.**