All of the following are topically used sulfonamides EXCEPT:
Correct Answer: Sulfasalazine
Description: SULFONAMIDES: 1 . Sho acting ( 4-8 hr ): Sulfadiazine 2. Intermediate acting (8-12 hr ): Sulfamethm,azole 3. Long acting ( -7 days): Sulfadoxine, Sulfamethopyrazine 4. Special purpose sulfonamides: Sulfacetamide sod, Mafenide, Silver sulfadiazine, Sulfasalazine. Sulfasalazine (Salicylazosulfapyridine) It is a compound of 5-aminosalicylic acid (5-ASA) with sulfapyridine linked through an azo bond that has a specific therapeutic effect in inflammatory bowel diseases (IBDs) like ulcerative colitis and Crohn&;s disease.They are both locally and systemically acting agents. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SIXTH EDITION PAGE NO:661
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