**Core Concept**
Favre-Goldmann syndrome is a rare, autosomal dominant disorder characterized by posterior subcapsular cataracts, glaucoma, and myopia. It is associated with mutations in the B3GAT1 gene, which encodes a glycosyltransferase enzyme involved in the synthesis of chondroitin sulfate proteoglycans in the cornea.
**Why the Correct Answer is Right**
Favre-Goldmann syndrome is characterized by the development of posterior subcapsular cataracts, which are thought to result from the abnormal glycosylation of proteins in the lens. The syndrome also commonly presents with glaucoma, which may be due to the abnormal corneal structure and function. Myopia, or nearsightedness, is another characteristic feature of Favre-Goldmann syndrome.
**Why Each Wrong Option is Incorrect**
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**Clinical Pearl / High-Yield Fact**
Favre-Goldmann syndrome is an important consideration in patients presenting with posterior subcapsular cataracts and glaucoma, particularly if there is a family history of the disorder.
**Correct Answer:**
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