All of the following are histopathological findings of papillary carcinoma, except
Correct Answer: Monofocal papillary projections
Description: Pathology
Papillary projections
Psammoma bodies (concentric calcifications)
Pale empty (orphan annie) nuclei → FINELY DISPERSED CHROMATIN IMPARTS AN EMPTY APPEARANCE
Intranuclear grooves and nuclear characteristics are diagnostic of papillary carcinoma
Multifocality is common in papillary carcinoma
TSH levels are high; tumors are TSH dependent, hence follow-up with TSH.
Key Concept:
Multifocality is common (up to 85% of cases) on microscopic examination.
Multifocality is associated with an increased risk of cervical nodal metastases, rarely invade adjacent structures such as the trachea, esophagus, and RLNs.
RLN implies lymph nodes.
Category:
Surgery
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