All of the following are features of streptomycin drug except:
**Core Concept**
Streptomycin is an aminoglycoside antibiotic that works by inhibiting bacterial protein synthesis. It binds to the 30S subunit of the bacterial ribosome, causing misreading of mRNA and leading to the production of aberrant proteins.
**Why the Correct Answer is Right**
Streptomycin's mechanism of action involves binding to the 30S subunit, which is a critical step in protein synthesis. This binding causes a conformational change in the ribosome, leading to the misreading of mRNA and the production of aberrant proteins. As a result, bacterial protein synthesis is inhibited, leading to bacterial death.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because aminoglycosides like streptomycin do not exhibit this characteristic. Aminoglycosides do not inhibit cell wall synthesis.
**Option B:** Incorrect because streptomycin is not an example of this class of drugs. Beta-lactam antibiotics, such as penicillin, inhibit cell wall synthesis.
**Option C:** Incorrect because streptomycin does not exhibit this characteristic. Aminoglycosides do not inhibit DNA replication.
**Clinical Pearl / High-Yield Fact**
Aminoglycosides, including streptomycin, can cause nephrotoxicity and ototoxicity as side effects. These side effects are dose-dependent and can be minimized by monitoring serum levels and using the lowest effective dose.
**Correct Answer: D.**