All of the following are feature of malignant hypeension except –
Correct Answer: Respiratory failure
Description: Hypeension is described as being in accelerated phase or MALIGNANT HYPEENSION when it causes acute damage to renal and other aerioles. It is often symptomatic, with headache, impaired vision and, finally, manifestations of renal failure Severe hypeensive retinopathy with papilloedema is almost always present.Malignant hypeension is a syndrome associated with an abrupt increase of blood pressure in a patient with underlying hypeension or related to the sudden onset of hypeension in a previously normotensive individual. The absolute level of blood pressure is not as impoant as its rate of rise. Pathologically, the syndrome is associated with diffuse necrotizing vasculitis, aeriolar thrombi, and fibrin deposition in aeriolar walls. Fibrinoid necrosis has been observed in aerioles of kidney, brain, retina, and other organs. Clinically, the syndrome is recognized byprogressive retinopathy (aeriolar spasm, hemorrhages, exudates,and papilledema), deteriorating renal function with proteinuria,microangiopathic hemolytic anemia, and encephalopathy.In these patients, historic inquiry should include questions about the use of monamine oxidase inhibitors and recreational drugs (e.g., cocaine, amphetamines). ref:Harrison&;s principles of internal medicine,ed 18,pg no 2058
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