Triple test It is a combined biochemical test which includes MSAFP,hCG,UE3(unconjugated oestriol).Maternal age in relation to confirmed gestational age is also taken into account.It is used for the detection of Down&;s syndrome.In an affected pregnancy,level of MSAFP and UE3 tend to be low while that of hCG is high.It is performed in 15-18 weeks. D.C.DUTTA&;S TEXTBOOK OF OBSTETRICS,pg no:106,7th edition