All of the following anti-microbials show Concentration dependent Killing except

Correct Answer: Penicillin G
Description: * Time dependent killing(TDK) : Here, the killing activity depends upon the length of time, plasma concentration is above MIC. It is shown by:* Beta Lactams.* Vancomycin* Concentration dependent killing(CDK) : Here, killing activity depends upon the ratio of plasma concentration to MIC.It is shown by:* Aminoglycosides.* Flouroquinolone* MetronidazoleTDK and CDK mainly apply to cidal drugs.So, Penicillin G is beta lactam and follows TDK.
Category: Pharmacology
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