All are true statements about anticancer drugs except?
Correct Answer: Irinotecan is a topoisomerase II inhibitor
Description: Anthracyclines cause cardiotoxicity, prevented by dexrazoxane Bleomycin causes pulmonary fibrosis L-asparaginase cause allergy, acute pancreatitis Vincristine, vinblastine causes peripheral neuropathy & SIADH. But it is marrow sparing. Irinotecan is a topoisomerase I inhibitor used for colorectal carcinoma Topoisomerase II inhibitors are Etoposide, doxorubicin, Daunorubicin & anthracyclines.
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