**Question:** All are true statements about Meckel's diverticulum except:

A. Meckel's diverticulum is a congenital remnant of the omphalomesenteric duct.
B. It is most common in females.
C. It is usually asymptomatic and diagnosed incidentally during surgery.
D. It is associated with a high risk of malignant tumors.

**Correct Answer:** B. It is most common in females.

**Core Concept:** Meckel's diverticulum is a congenital anomaly that occurs when a portion of the omphalomesenteric duct fails to regress during fetal development. This results in a pouch-like structure that protrudes from the antimesenteric border of the distal small intestine, typically in the ileum.

**Why the Correct Answer is Right:** Meckel's diverticulum is predominantly found in males since the omphalomesenteric duct is more commonly retained in males due to genetic factors. It is estimated that the prevalence of Meckel's diverticulum is 1-2% among the general population.

**Why Each Wrong Option is Incorrect:**

A. Meckel's diverticulum is a congenital remnant of the omphalomesenteric duct, which is consistent with the correct statement.

B. The statement that Meckel's diverticulum is most common in females is incorrect. As mentioned earlier, it is more prevalent in males due to genetic factors.

C. Meckel's diverticulum is usually asymptomatic and diagnosed incidentally during surgery. This statement highlights the importance of recognizing this condition, as it may present with complications such as gastrointestinal bleeding, intestinal obstruction, and, rarely, malignant tumors.

D. Meckel's diverticulum is associated with a high risk of malignant tumors is partially correct. While it is true that Meckel's diverticulum carries a higher risk of malignant tumors (often adenocarcinomas) compared to the general population, the statement is misleading because Meckel's diverticulum is still relatively rare, with an estimated risk of malignant potential ranging from 0.3-3.7%.

**Clinical Pearl:** Meckel's diverticulum, although a rare cause of gastrointestinal bleeding and intestinal obstruction, is generally considered a benign condition when diagnosed incidentally during surgery. However, it is essential for clinicians to be aware of its potential for malignant degeneration, especially for proper management and follow-up strategies.