**Core Concept**
Malaria is a mosquito-borne infectious disease caused by Plasmodium parasites, transmitted through the bite of an infected female Anopheles mosquito. The disease presents with a wide range of clinical manifestations, from asymptomatic infection to severe complications such as cerebral malaria.

**Why the Correct Answer is Right**
Malaria is characterized by a complex life cycle involving two hosts: the mosquito and the human. The parasite undergoes asexual reproduction in the human host, leading to the symptoms of the disease. The most severe form of malaria is caused by Plasmodium falciparum, which can lead to cerebral malaria, a life-threatening complication.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it is a true statement regarding malaria. Malaria is caused by Plasmodium parasites, which are transmitted through the bite of an infected female Anopheles mosquito.
**Option B:** This option is incorrect because it is a true statement regarding malaria. The disease is characterized by a wide range of clinical manifestations, from asymptomatic infection to severe complications such as cerebral malaria.
**Option C:** This option is incorrect because it is a true statement regarding malaria. The parasite undergoes asexual reproduction in the human host, leading to the symptoms of the disease.

**Clinical Pearl / High-Yield Fact**
One of the most critical factors in the diagnosis of malaria is the rapid detection of the parasite in the blood, which can be achieved through microscopy or rapid diagnostic tests. Early detection and treatment are essential in preventing complications and reducing mortality.

**Correct Answer:**
( Wait for the correct options to complete the question )