**Question:** All are true regarding Fronto-temporal dementia except:

A. Fronto-temporal dementia (FTD) is a rare form of dementia.
B. Alzheimer's disease is the most common cause of dementia in individuals over 65 years.
C. FTD primarily affects older adults.
D. FTD is associated with memory loss.

**Correct Answer:**

**Core Concept:** Fronto-temporal dementia (FTD) is a subtype of dementia that primarily affects the frontal and temporal lobes of the brain. It is characterized by behavioral and personality changes, rather than memory loss, making it distinct from Alzheimer's disease.

**Why the Correct Answer is Right:**

FTD is indeed a rare form of dementia, accounting for around 10-15% of dementia cases under 65 years. While Alzheimer's disease is the most common cause of dementia in individuals over 65 years, FTD affects a younger population. FTD is primarily associated with behavioral and personality changes, rather than memory loss, which is a key feature of Alzheimer's disease.

**Why Each Wrong Option is Incorrect:**

A. Although FTD can occur in individuals of any age, the misconception that it is a rare form of dementia is incorrect. The correct answer highlights this fact.

B. The statement "Alzheimer's disease is the most common cause of dementia in individuals over 65 years" is true, but it does not negate the fact that FTD is also a cause of dementia in that age group.

C. While FTD does affect individuals of all ages, the statement "FTD primarily affects older adults" is misleading, highlighting the misconception that FTD is mainly an old-age condition.

D. Memory loss is not a key feature of FTD; instead, behavioral and personality changes are the primary symptoms. This option highlights the correct understanding of FTD's clinical presentation.

**Clinical Pearl:** Understanding the distinct clinical presentation and age spectrum of Fronto-temporal dementia can help differentiate it from other dementia subtypes, such as Alzheimer's disease, particularly in the younger population. This understanding is crucial for appropriate diagnosis and management of patients with dementia.