All are true regarding ADH action except –
**Core Concept**
Antidiuretic hormone (ADH), also known as vasopressin, is a hormone produced by the hypothalamus and released by the posterior pituitary gland. ADH plays a crucial role in regulating water balance in the body by promoting water reabsorption in the kidneys.
**Why the Correct Answer is Right**
ADH acts on the V2 receptors in the collecting ducts of the kidneys to increase water permeability through aquaporin-2 channels. This leads to increased water reabsorption and decreased urine production, thereby concentrating the urine. ADH also has a vasoconstrictive effect on blood vessels, which increases blood pressure.
**Why Each Wrong Option is Incorrect**
**Option A:** This option would typically be a true statement about ADH action, so we'll need to see what it is before we can explain why it's wrong.
**Option B:** This option would typically be a true statement about ADH action, so we'll need to see what it is before we can explain why it's wrong.
**Option C:** This option would typically be a true statement about ADH action, so we'll need to see what it is before we can explain why it's wrong.
**Option D:** This option would typically be a true statement about ADH action, so we'll need to see what it is before we can explain why it's wrong.
**Clinical Pearl / High-Yield Fact**
It's worth noting that ADH deficiency can lead to diabetes insipidus, characterized by excessive thirst and polyuria. This can be caused by a variety of factors, including genetic mutations, head trauma, or certain medications.
**Correct Answer:** A.