**Core Concept**
Ulcerative colitis (UC) is a type of inflammatory bowel disease characterized by chronic inflammation and ulceration of the colonic mucosa. It is associated with various extraintestinal manifestations and complications due to its complex pathophysiology.
**Why the Correct Answer is Right**
Ulcerative colitis is associated with an increased risk of primary sclerosing cholangitis (PSC), a chronic liver disease characterized by inflammation and fibrosis of the bile ducts. This association is thought to be related to the shared genetic predisposition and the common underlying immune dysregulation. Additionally, UC is associated with an increased risk of colorectal cancer, particularly in patients with extensive colitis and long-standing disease.
**Why Each Wrong Option is Incorrect**
**Option A:**
*Not provided*
**Option B:**
*Not provided*
**Option C:**
*Not provided*
**Clinical Pearl / High-Yield Fact**
It's essential to recognize the extraintestinal manifestations of UC, including primary sclerosing cholangitis, to provide comprehensive care and monitor for potential complications. A thorough medical history and physical examination can help identify these associations.
**Correct Answer: A. B. C.**
Free Medical MCQs · NEET PG · USMLE · AIIMS
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