All are true about Turner syndrome except
**Core Concept**
Turner syndrome is a genetic disorder that affects females, characterized by the partial or complete absence of one X chromosome. It is a chromosomal abnormality that leads to a range of physical and developmental issues.
**Why the Correct Answer is Right**
Turner syndrome is associated with short stature, ovarian dysgenesis, and infertility. The absence of one X chromosome disrupts the normal development of the ovaries, leading to a lack of estrogen production and subsequent stunted growth. Individuals with Turner syndrome often have characteristic physical features, including a short neck, low-set ears, and a broad chest.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because Turner syndrome is not typically associated with an increased risk of breast cancer. In fact, individuals with Turner syndrome often have a decreased risk of breast cancer due to the lack of estrogen production.
**Option B:** This option is incorrect because Turner syndrome is not typically associated with an increased risk of thrombosis. While individuals with Turner syndrome may have an increased risk of cardiovascular disease, this is not directly related to thrombosis.
**Option C:** This option is incorrect because Turner syndrome is not typically associated with an increased risk of type 1 diabetes. However, individuals with Turner syndrome may have an increased risk of autoimmune disorders, including Hashimoto's thyroiditis.
**Clinical Pearl / High-Yield Fact**
Individuals with Turner syndrome often have a characteristic "shield chest" deformity, which is a result of the absence of one X chromosome disrupting normal breast development.
**Correct Answer: A. Turner syndrome is not typically associated with an increased risk of breast cancer.**