All are TRUE about the clinical features of polycythemia rubra vera, EXCEPT:
Correct Answer: Hepatomegaly is the initial presenting sign
Description: Polycythemia rubra vera clinical features: Splenomegaly may be the initial presenting sign Aquagenic pruritus Hyperviscosity leads to veigo, tinnitus, headache, visual disturbances, and transient ischemic attacks (TIAs). Systolic hypeension is due to red cell mass elevation. Venous or aerial thrombosis may be the presenting manifestation of PV. Erythromelalgia, is a complication of the thrombocytosis Hyperuricemia with secondary gout, uric acid stones, and symptoms due to hypermetabolism can also complicate the disorder. Ref: Harrison, E-18, P-899
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