**Question:** All are true about Syndrome X EXCEPT:

A. Syndrome X is a term used to describe a group of symptoms and signs in patients with coronary artery disease (CAD) that include ischemic chest pain, hypertension, dyslipidemia, and impaired fasting glucose.
B. The presence of insulin resistance and/or impaired glucose tolerance is a key feature of Syndrome X.
C. The syndrome is primarily seen in women, with a female-to-male ratio of 3:1.
D. Syndrome X is associated with increased mortality and morbidity due to CAD.

**Correct Answer:** C. Syndrome X is primarily seen in women, with a female-to-male ratio of 3:1.

**Core Concept:** Syndrome X is a clinical entity characterized by a cluster of symptoms and signs in patients with coronary artery disease (CAD). The syndrome includes ischemic chest pain, hypertension, dyslipidemia, and impaired fasting glucose. Insulin resistance and/or impaired glucose tolerance are key features of Syndrome X, contributing to its association with increased risk for cardiovascular events and mortality.

**Why the Correct Answer is Right:** The correct answer (C) is right because Syndrome X is not exclusively seen in females. While it is true that Syndrome X is more common in females, the statement that it is "primarily seen in women with a female-to-male ratio of 3:1 is incorrect. Syndrome X affects both genders, and this ratio is not representative of its prevalence.

**Why Each Wrong Option is Incorrect:**

A. While Syndrome X does encompass the symptoms and signs mentioned (ischemic chest pain, hypertension, dyslipidemia, and impaired fasting glucose), the statement that it is a term used merely to describe a group of symptoms is incorrect. Syndrome X is a recognized clinical entity with a specific pathological basis, involving insulin resistance and/or impaired glucose tolerance.

B. The presence of insulin resistance and impaired glucose tolerance are essential features of Syndrome X, contributing to its association with increased cardiovascular risk. The statement that Syndrome X is seen primarily in women is incorrect. Syndrome X affects both genders.

**Why the Correct Answer is Right:** Syndrome X is characterized by the presence of insulin resistance and impaired glucose tolerance, which contribute to its association with increased cardiovascular risk. This is why the correct answer (C) is right: Syndrome X affects both genders, not just women, and its association with cardiovascular risk is due to the presence of insulin resistance and impaired glucose tolerance.

**Why Each Wrong Option is Incorrect:**

A. The presence of insulin resistance and impaired glucose tolerance are essential features of Syndrome X, contributing to its association with increased cardiovascular risk. The statement that Syndrome X is associated with a female-to-male ratio of 3:1 is incorrect. Syndrome X affects both genders, not just women.

B. While it is true that Syndrome X is characterized by insulin resistance and impaired glucose tolerance, the statement that Syndrome X is primarily seen in women is incorrect. Syndrome X affects both genders.

**Why Each Wrong Option is Incorrect:**

C