All are true about propionibacterium acne except
**Core Concept**
Propionibacterium acnes (P. acnes) is a gram-positive, anaerobic bacterium that is a major contributor to the development of acne vulgaris. It is a normal inhabitant of the skin and thrives in the pilosebaceous unit, where it contributes to inflammation and comedone formation.
**Why the Correct Answer is Right**
P. acnes produces lipases that break down triglycerides into free fatty acids and glycerol, leading to inflammation and comedone formation. It also produces porphyrins, which are responsible for the characteristic blue-black pigmentation seen in acne scars. P. acnes is sensitive to antibiotics such as erythromycin and clindamycin, which are commonly used in the treatment of acne.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because P. acnes is not typically associated with the development of abscesses or cellulitis, which are more commonly caused by Staphylococcus aureus.
**Option B:** This option is incorrect because P. acnes is not typically resistant to metronidazole, which is an antibiotic commonly used to treat bacterial vaginosis and other anaerobic infections.
**Option C:** This option is incorrect because P. acnes is not typically associated with the development of septicemia or bacteremia, which are more commonly caused by virulent bacteria such as Staphylococcus aureus.
**Clinical Pearl / High-Yield Fact**
P. acnes is a normal inhabitant of the skin and can be cultured from the skin of healthy individuals. However, its presence is often increased in individuals with acne, and it is a major contributor to the development of this condition.
**Correct Answer:**
(There is no correct answer provided, please provide the correct answer and I'll be happy to assist further)