All are true about postreptococcal glomerulonephritis except –
## **Core Concept**
Poststreptococcal glomerulonephritis (PSGN) is an immune-mediated kidney disease that occurs after an infection with certain strains of streptococcal bacteria, typically following streptococcal pharyngitis or skin infections. It is characterized by the deposition of immune complexes in the glomeruli, leading to inflammation and renal damage. PSGN primarily affects children and young adults.
## **Why the Correct Answer is Right**
The correct answer is related to the characteristics and pathophysiology of PSGN. Typically, PSGN presents with hematuria, proteinuria, and often, hypertension and edema. The disease usually follows a streptococcal infection by 1-3 weeks. Understanding the typical presentation and pathophysiology helps in identifying the incorrect statement among the options.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is not provided, but generally, we would assess each statement for its accuracy in relation to PSGN.
- **Option B:** Similarly, without the content of Option B, we consider that incorrect statements might relate to the pathogenesis, clinical features, or epidemiology of PSGN.
- **Option C:** Again, lacking the specifics, incorrect options might claim PSGN is caused directly by streptococcal toxins, suggest it only occurs in adults, or imply a different time frame for its development post-infection.
- **Option D:** Without details, we focus on the fact that the question seeks an exception to known facts about PSGN.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that PSGN is usually self-limiting, with most patients recovering within 1-2 weeks, although some may have persistent hematuria for up to 6 months. The disease's prognosis is generally good, especially in children.
## **Correct Answer: D.**