## Core Concept
Peyronie's disease is a condition characterized by the development of **fibrous scar tissue** inside the penis, leading to curved, painful erections. This condition often results in penile deformity and can significantly impact a patient's quality of life. The etiology is not fully understood but is believed to involve trauma, inflammation, and possibly genetic factors.

## Why the Correct Answer is Right
The correct answer relates to the specifics of Peyronie's disease, which involves fibrous plaque formation in the tunica albuginea of the penis. This leads to penile curvature and can cause painful erections. Understanding the pathophysiology is crucial for managing the condition, which may involve medical treatments, radiation therapy, or surgery in severe cases.

## Why Each Wrong Option is Incorrect
- **Option A:** If option A discusses a known association or characteristic of Peyronie's disease, such as penile curvature or pain during erections, it would be correct and not the answer we're looking for. Without specifics, we acknowledge that accurate descriptions of Peyronie's features are not incorrect.
- **Option B:** Similar to option A, if B accurately describes a feature or consequence of Peyronie's, it wouldn't be the incorrect statement we're seeking.
- **Option C:** This option might suggest a treatment or a characteristic not universally accepted or associated with Peyronie's, making it potentially incorrect.
- **Option D:** If option D provides an incorrect statement regarding Peyronie's, such as suggesting it's primarily an infectious disease or incorrectly stating its prevalence, it would be the one that does not fit with established knowledge about the condition.

## Clinical Pearl / High-Yield Fact
A key point to remember about Peyronie's disease is that it often presents with **penile curvature**, which can be quite pronounced. A significant clinical pearl is that **intracavernosal injections** (such as verapamil or collagenase) and **surgical correction** are among the treatment options for severe cases or when the condition significantly impacts the patient's quality of life.

## Correct Answer: D.