All are TRUE about paroxysmal cold hemoglobinuria (PCH), EXCEPT:

Correct Answer: Lysis of blood cells occur only at low temperature
Description: Paroxysmal cold hemoglobinuria is a rare form, occurs mostly in children, triggered by viral infection. Donath Landsteiner antibody binds to red cells only at low temperature, but lysis takes place when the temperature is shifted to 37 celcius. Ref: Harrison's principles of internal medicine, 18th edition; Page 882
Category: Medicine
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