All are true about Neisseria gonorrhoeae except
**Core Concept**
Neisseria gonorrhoeae is a Gram-negative, aerobic diplococcus bacterium that causes the sexually transmitted infection gonorrhea. It has a complex pathogenic mechanism involving adherence to host cells, invasion of mucosal surfaces, and evasion of the host immune response.
**Why the Correct Answer is Right**
The correct answer will be a statement that accurately describes a characteristic or behavior of Neisseria gonorrhoeae. This may involve its virulence factors, antibiotic resistance, or epidemiological features. For example, Neisseria gonorrhoeae has a unique ability to adhere to and invade mucosal surfaces, particularly in the cervix and urethra of infected individuals. This adherence is mediated by the bacteria's pili, which interact with host cell receptors such as glycoproteins.
**Why Each Wrong Option is Incorrect**
**Option A:** This statement is incorrect because Neisseria gonorrhoeae is not typically associated with respiratory infections in humans. While it can cause extragenital infections, such as pharyngitis or conjunctivitis, these are relatively rare and usually occur in individuals who have engaged in oral or genital-to-ocular contact with infected bodily fluids.
**Option B:** This statement is incorrect because Neisseria gonorrhoeae is not a leading cause of bacterial meningitis in adults. While it can cause sepsis and disseminated infection, this is typically seen in individuals with underlying immunocompromising conditions.
**Option C:** This statement is incorrect because Neisseria gonorrhoeae is not typically associated with the development of autoimmune disorders. However, it is possible for individuals infected with Neisseria gonorrhoeae to develop post-infectious complications, such as reactive arthritis or urethritis.
**Clinical Pearl / High-Yield Fact**
The Centers for Disease Control and Prevention (CDC) recommend dual antibiotic therapy for the treatment of gonorrhea, involving a combination of ceftriaxone and azithromycin. This is due to the increasing prevalence of antibiotic-resistant strains of Neisseria gonorrhoeae.
**Correct Answer:** None provided