All are TRUE about myxomas in hea, EXCEPT:
**Core Concept**
Myxomas are rare, benign cardiac tumors that can arise in the atria, most commonly in the left atrium. They are composed of mesenchymal cells and can cause various symptoms due to their location and potential for embolization.
**Why the Correct Answer is Right**
Myxomas can present with a range of clinical manifestations, including obstructive symptoms, embolic events, and systemic symptoms such as fever and weight loss. The most common presentation is a left atrial mass, which can be visualized on echocardiography. Myxomas can also be associated with a specific clinical syndrome known as the "Osler-Rendu-Weber syndrome" or Carney complex, which is characterized by multiple endocrine tumors and cutaneous and mucosal myxomas.
**Why Each Wrong Option is Incorrect**
**Option A:** Myxomas are indeed most commonly found in the left atrium, so this statement is true.
**Option B:** Myxomas can cause embolic events, so this statement is also true.
**Option C:** Myxomas can be associated with systemic symptoms such as fever and weight loss, making this statement true as well.
**Clinical Pearl / High-Yield Fact**
A key clinical feature of myxomas is their potential for embolization, which can lead to a range of symptoms including stroke, peripheral artery disease, and other systemic complications. Clinicians should be aware of this risk and consider echocardiography in patients with unexplained embolic events.
**Correct Answer:** D.