Microbiology All are true about Immune Reconstitution Inflammatory syndrome (IRIS) except: A It occurs when CD4 cell count is < 50 cells/mm3 B Develops after initiation of anti-retroviral therapy C Associated with delayed type of hypersensitivity D Does not require a specific antimicrobial therapy for recovery 💡 Explanation All are true about Immune Reconstitution Inflammatory syndrome (IRIS) except: ✓ Correct Answer: A. It occurs when CD4 cell count is < 50 cells/mm3