All are true about hepatoblastoma except
**Core Concept**
Hepatoblastoma is a rare malignant liver tumor that typically affects children, representing the most common primary liver cancer in this age group. It arises from embryonal liver cells, exhibiting a unique histopathological profile.
**Why the Correct Answer is Right**
Hepatoblastoma often presents with abdominal distension, vomiting, and loss of appetite in infants and children. The tumor's growth can lead to liver dysfunction, and metastasis to lungs, bones, or other organs is not uncommon. The management of hepatoblastoma involves a multidisciplinary approach, including surgical resection, chemotherapy, and in some cases, liver transplantation.
**Why Each Wrong Option is Incorrect**
**Option A:** Hepatoblastoma is not typically associated with cirrhosis.
Hepatoblastoma arises from embryonal liver cells, not from pre-existing cirrhotic tissue.
**Option B:** Hepatoblastoma is not a benign tumor.
Hepatoblastoma is a malignant liver tumor with aggressive behavior, requiring prompt treatment.
**Option C:** Hepatoblastoma is not a tumor of the bile duct.
Hepatoblastoma arises from embryonal liver cells, not from the epithelial lining of the bile ducts.
**Option D:** Hepatoblastoma is not typically seen in adults.
Hepatoblastoma is a rare tumor primarily affecting children, with a peak incidence in early childhood.
**Clinical Pearl / High-Yield Fact**
The Children's Oncology Group (COG) has established a risk stratification system for hepatoblastoma, which guides treatment decisions and predicts outcomes.
**Correct Answer: D. Hepatoblastoma is not typically seen in adults.**