All are true about functional divisions of liver EXCEPT:
**Core Concept**
The liver is a complex organ with multiple functional divisions, each with distinct roles in metabolism, detoxification, and production of vital proteins. These divisions are based on the distribution of blood flow and the specific functions of the liver cells (hepatocytes) within different regions.
**Why the Correct Answer is Right**
The liver is traditionally divided into three main functional zones: the periportal zone, the midzonal area, and the pericentral zone. The periportal zone receives oxygenated blood from the hepatic artery and is involved in the metabolism of carbohydrates, proteins, and fats. The midzonal area receives blood from both the hepatic artery and the portal vein and is involved in the metabolism of lipids and the production of bile. The pericentral zone receives blood from the portal vein and is involved in the metabolism of toxic substances and the production of urea.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately describe a functional division of the liver.
**Option B:** This option is incorrect because it does not correctly identify the periportal zone's role in metabolism.
**Option C:** This option is incorrect because it does not accurately describe the pericentral zone's role in metabolism.
**Clinical Pearl / High-Yield Fact**
The liver's functional divisions are crucial for understanding liver disease, as damage to specific zones can lead to distinct clinical manifestations. For example, damage to the periportal zone can lead to impaired glucose metabolism, while damage to the pericentral zone can lead to impaired detoxification.
**Correct Answer: A.**