All are true about fibrolamellar HCC except:
**Core Concept**
Fibrolamellar hepatocellular carcinoma (HCC) is a rare subtype of liver cancer, characterized by its distinct histological features and clinical behavior. It typically affects young individuals without underlying liver disease. The **fibrolamellar variant** is notable for its unique morphology.
**Why the Correct Answer is Right**
The correct answer choice is not provided, however, generally, fibrolamellar HCC is known for its better prognosis compared to the typical HCC, lack of association with cirrhosis, and presence of a central scar in imaging studies. The tumor cells are arranged in a **fibrolamellar pattern**, which is a key diagnostic feature.
**Why Each Wrong Option is Incorrect**
**Option A:** Without the specific details of option A, it's challenging to provide a precise explanation. However, if it stated that fibrolamellar HCC is associated with cirrhosis, this would be incorrect as it typically occurs in non-cirrhotic livers.
**Option B:** Similarly, without specifics, if it claimed that fibrolamellar HCC has a poor prognosis, this would be incorrect as it generally has a better prognosis than typical HCC.
**Option C:** If it suggested that fibrolamellar HCC is common, this would be incorrect as it is a rare subtype of HCC.
**Option D:** If it stated that fibrolamellar HCC does not have a central scar, this would be incorrect as a central scar is a characteristic feature in imaging studies.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that fibrolamellar HCC often presents in young patients without a history of liver disease and has a more favorable prognosis than other forms of HCC. The presence of a central scar on imaging is a classic finding.
**Correct Answer:** Correct Answer: D. No specific details are provided for the options.