All are true about Autoimmune disease except ?
Correct Answer: Higher incidence among males
Description: Ans. is 'c' i.e.Higher incidence among male The essential feature of an autoimmune disease is that tissue injury is caused by the immunologic reaction of the organism with its own tissues. Autoimmunity, on the other hand, refers merely to the presence of antibodies or T lymphocytes that react with self- antigens and does not necessarily imply that the development of self reactivity has pathogenic consequences. . Autoimmune diseases are syndromes caused by the activation of T or B cells or both, with no evidence of other causes such as infections or malignancies. Intense stimulation of T lymphocytes can produce nonspecific signals that bypass the need for antigen-specific helper T cells and lead to polyclonal Bcell activation with the formation of multiple autoantibodies. . It is now known that low levels of autoreactivity of T and B cells with self- antigens in the periphery are critical to their survival. . Co-stimulatory molecules such as B7-1 (CD80) or B7-2(CD86)are involved in autoimmunity. . Higher incidence among female-Ananthnarayan 8th/172 . Hashimoto's thyroiditis is an autoimmune disorder.
Category:
Microbiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now