All are true about atropine poisoning, except FMGE 11
**Core Concept**
Atropine poisoning is a condition caused by excessive intake of atropine, a medication that belongs to the anticholinergic class of drugs. It leads to a reversal of parasympathetic tone, causing a range of systemic and central nervous system effects.
**Why the Correct Answer is Right**
Atropine poisoning results from the blockade of muscarinic acetylcholine receptors in the central and peripheral nervous system. This blockade leads to increased heart rate, dilated pupils, dry mouth, and decreased bowel sounds. Additionally, atropine can cause central nervous system effects such as delirium, hallucinations, and coma due to its ability to cross the blood-brain barrier.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because atropine poisoning is characterized by tachycardia, not bradycardia.
**Option B:** Incorrect because dry mouth (xerostomia) is a classic symptom of atropine poisoning due to its anticholinergic effects.
**Option C:** Incorrect because mydriasis (dilated pupils) is a well-documented effect of atropine poisoning.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that atropine poisoning can lead to a range of systemic effects, including tachycardia, dry mouth, and mydriasis, and that it can be life-threatening if not managed promptly.
**Correct Answer: D.**