All are true about amoebic ulcer except
**Question:** All are true about amoebic ulcer except
A. Amoebic ulcer is characterized by a solitary, deep, painful ulcer with a surrounding edematous margin.
B. It commonly occurs in immunocompromised individuals.
C. The causative agent is the protozoan Entamoeba histolytica.
D. The diagnosis is confirmed by serology alone.
**Correct Answer:** D. The diagnosis is confirmed by serology alone.
**Core Concept:** Amoebic ulcer is a type of intestinal infection caused by the protozoan Entamoeba histolytica, which can lead to the formation of painful ulcers. These ulcers often present as solitary, deep, and edematous lesions. The disease primarily affects immunocompetent individuals and is not related to immune system status.
**Why the Correct Answer is Right:**
Amoebic ulcer diagnosis typically involves a combination of clinical presentation, serological tests, and stool examination. While serology is a useful tool for confirming the presence of antibodies against E. histolytica, it is not sufficient for diagnosis by itself. Serology can indicate infection but may not always confirm the presence of the actual parasite in the patient's stool.
**Why Each Wrong Option is Incorrect:**
A. This option is correct as amoebic ulcer is characterized by a solitary, deep, painful ulcer with a surrounding edematous margin.
B. This option is incorrect because amoebic ulcer affects immunocompetent individuals, not immunocompromised ones.
C. This option is correct as the causative agent of amoebic ulcer is Entamoeba histolytica, a protozoan parasite.
**Clinical Pearl:**
Amoebic ulcer is a crucial diagnosis to make as it can be confused with other conditions like tuberculosis and malignancies. A thorough clinical examination, including stool examination for Entamoeba histolytica, is essential for accurate diagnosis. Serological tests can help confirm the presence of antibodies but should not be relied on solely. A combination of clinical presentation, serology, and stool examination is crucial for a definitive diagnosis and appropriate treatment.