Criteria of Unresectability in Hilar cholangiocarcinoma Hepatic duct involvement upto secondary radicals bilaterally Encasement or occlusion of the main poal vein proximal to its bifurcation Atrophy of one lobe with encasement of contralateral poal vein branch Atrophy of one lobe with contralateral involvement of secondary biliary radicals Histologically proven metastasis to N2 lymph nodes Liver, lung or peritoneal metastasis In hilar cholangiocarcinoma, several early branches of left hepatic duct drain the caudate lobe and can be involved early with the tumor Consideration for routine caudate Lobectomy should be made in these cases Ref: Sabiston 20th edition Pgno :1514-1518