All are complications of diphtheria except –
**Core Concept:** Diphtheria is a severe infectious disease caused by the bacterium Corynebacterium diphtheriae. It primarily affects the respiratory system, leading to respiratory distress and myocarditis. Antibodies against diphtheria toxin are essential for the immune response against the disease.
**Why the Correct Answer is Right:** The correct answer refers to complications of diphtheria, which are mainly due to the toxin produced by the bacterium. The toxin causes myocarditis, peripheral neuropathy, and, in severe cases, respiratory distress. The correct answer (None of the options) highlights that these complications are part of diphtheria's presentation, not as complications.
**Why Each Wrong Option is Incorrect:**
A. **Neuromuscular paralysis (polyneuropathy)**: This complication is caused by the toxin produced by C. diphtheriae. However, this is a correct complication and not the answer to the question.
B. **Myocarditis**: Myocarditis is caused by the toxin and is a correct complication of diphtheria. It results in heart muscle inflammation and can lead to heart failure.
C. **Respiratory distress**: Diphtheria toxin can lead to respiratory distress due to the inflammation and obstruction caused by the toxin in the respiratory tract. This is a correct complication.
D. **Encephalitis**: Encephalitis is not a complication of diphtheria. It is a complication of other infections, such as viral meningitis.
**Clinical Pearl:**
Diphtheria is a serious infection that can lead to life-threatening complications, such as myocarditis, respiratory distress, and neuropathy. Appropriate vaccination and treatment with antitoxin can prevent severe complications and save lives. Understanding the toxin's role in the disease and its complications is essential for determining the correct answer.