All are anti-craving agents for alcohol except
Correct Answer: Lorazepam
Description: Anti-craving agentsAcamprosate, naltrexone and SSRIs (such as fluoxetine) are among the medications tried as anti-craving agents in alcohol dependence. Acamprosate (the Ca++ salt of N-acetyl-homo taurinate) interacts with NMDA receptor-mediated glutamatergic neurotransmission in the various brain regions and reduces Ca++ fluxes through voltage-operatedchannels. Naltrexone (oral opioid receptor antagonist) probably interferes with alcohol-induced reinforcement by blocking opioid receptors. Fluoxetine (and other SSRIs) have been occasionally used as anti-craving agents in their usual antidepressant doses. Ref: A Sho Textbook of Psychiatry, Niraj Ahuja, 7th Edition, pg. no.42 Lorazepam is a benzodiazepine class of drug used for the treatment of alcohol withdrawal.
Category:
Psychiatry
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