**Core Concept**
The question is testing the knowledge of pharmacological management of alcohol withdrawal symptoms, specifically the choice of medication to prevent or alleviate withdrawal symptoms in individuals undergoing alcohol detoxification.

**Why the Correct Answer is Right**
The correct answer is Benzodiazepines. Benzodiazepines act on the GABA_A receptor, enhancing the effect of the neurotransmitter GABA (gamma-aminobutyric acid), which has a calming effect on the nervous system. This reduces the activity of neurons, leading to a decrease in the symptoms of alcohol withdrawal, such as anxiety, tremors, and seizures. Benzodiazepines, such as diazepam (Valium) and chlordiazepoxide (Librium), are the preferred choice for managing alcohol withdrawal due to their efficacy in reducing withdrawal symptoms and preventing seizures.

**Why Each Wrong Option is Incorrect**
**Option A:** is incorrect because Antipsychotics, such as haloperidol, are not the first-line treatment for alcohol withdrawal. While they may be used to manage agitation or aggression, they can have adverse effects, such as extrapyramidal symptoms, and are not as effective in preventing seizures as benzodiazepines.

**Option B:** is incorrect because Anticonvulsants, such as phenobarbital, may be used in the management of alcohol withdrawal, but they are not the first-line treatment. Anticonvulsants can be used to prevent seizures, but they do not address the full spectrum of withdrawal symptoms as effectively as benzodiazepines.

**Option C:** is incorrect because Opioid antagonists, such as naloxone, are not used to treat alcohol withdrawal. Naloxone is used to reverse opioid overdose and is not effective in managing withdrawal symptoms.

**Clinical Pearl / High-Yield Fact**
It is essential to note that benzodiazepines should be used with caution in patients with a history of substance abuse or those who are at risk of developing dependence. A tapering regimen should be used to minimize the risk of withdrawal symptoms when discontinuing benzodiazepines.

**Correct Answer:** C.