Alcohol Dehydrogenase comes under which class of enzyme?
**Core Concept**
Alcohol Dehydrogenase (ADH) is an enzyme responsible for the oxidation of alcohols to their corresponding aldehydes or ketones in the presence of NAD+ as a cofactor. This reaction is a crucial step in the metabolism of various alcohols, including ethanol, methanol, and isopropanol.
**Why the Correct Answer is Right**
Alcohol Dehydrogenase belongs to the class of enzymes known as oxidoreductases, specifically the subfamily of NAD+-dependent oxidoreductases. This enzyme catalyzes the transfer of a hydride ion from the substrate (alcohol) to NAD+, resulting in the formation of the corresponding aldehyde or ketone and NADH. The activity of ADH is crucial in the metabolism of alcohols and has implications in various clinical conditions, including alcohol dependence and alcohol-induced liver damage.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it does not specify the correct class of enzyme for Alcohol Dehydrogenase. While it may seem plausible, it lacks the necessary specificity.
**Option B:** This option is incorrect as it refers to a different class of enzymes altogether, unrelated to the metabolic function of Alcohol Dehydrogenase.
**Option C:** This option is incorrect as it does not accurately describe the class of enzyme for Alcohol Dehydrogenase. While it may seem similar, it lacks the necessary detail.
**Clinical Pearl / High-Yield Fact**
Alcohol Dehydrogenase is inhibited by certain compounds, such as fomepizole, which can be used to treat methanol poisoning. This is a critical clinical application of the enzyme's function and highlights the importance of understanding its metabolic role.
**Correct Answer: C. NAD+-dependent oxidoreductases.