## **Core Concept**
The question tests the association between various types of arthritis and uveitis, which is a form of eye inflammation. Uveitis is commonly linked with seronegative spondyloarthropathies. These are a group of diseases characterized by inflammatory arthritis and the absence of rheumatoid factor.

## **Why the Correct Answer is Right**
The correct answer, **Ankylosing Spondylitis (AS)**, is strongly associated with uveitis. AS is a type of seronegative spondyloarthropathy that primarily affects the spine, although other joints can be involved. The inflammation in AS can lead to uveitis, which is an inflammation of the uvea in the eye. This association is well-documented, and uveitis is a known extra-articular manifestation of AS.

## **Why Each Wrong Option is Incorrect**
- **Option A: Rheumatoid Arthritis (RA)**. While RA is a common form of arthritis, it is not typically associated with uveitis. RA can have various extra-articular manifestations, but uveitis is more commonly linked with spondyloarthropathies.
- **Option B: Osteoarthritis (OA)**. OA is a degenerative joint disease and is not typically associated with inflammatory conditions like uveitis. It does not have a significant link with uveitis.
- **Option C: Gout**. Gout is a form of arthritis characterized by acute, intermittent episodes of joint inflammation. It is not commonly associated with uveitis.

## **Clinical Pearl / High-Yield Fact**
A key clinical pearl is that **seronegative spondyloarthropathies**, such as **Ankylosing Spondylitis**, **Psoriatic Arthritis**, and **Reactive Arthritis**, have a strong association with **HLA-B27**. Uveitis, particularly anterior uveitis, is a common extra-articular feature of these diseases. Remembering this association can help in the diagnosis and management of patients with arthritis and uveitis.

## **Correct Answer: D. Ankylosing Spondylitis**