AH of the following are true about lymphocyte depletion variety of HL except:
Correct Answer: CD 20 expression
Description: Ans: b (CD 20 expression) Ref: Robbins, 7th ed, p. 688CD20 expression is classical of lymphocyte predominant variety of HL and not lymphocyte depletion variety.L & H variant is seen in lymphocyte predominant variety of HL and it classically expresses CD20 and germinal centre transcription factor BCL 6.HODGKIN LYMPHOMA (REAL CLASSIFICATION)|||Classical subtypes1) Nodular sclerosis2) Mixed cellularity3) Lymphocyte rich4) Lymphocyte depletionLymphocyte predominance(Distinct immunophenotype) SubtypesMorphologyImmunophenotypeNodular sclerosisLacunar variantsOccasional RS cellsCD 15 (+), CD 30(+)Mixed cellularityMononuclear variantRS cells (+)CD 15(+),CD 30(+)Lymphocyte richMononuclear variantRS cells (+)CD 15(+),CD 30(+)Lymphocyte depletionReticular variant(Pleomorphic variant)CD 15(+),CD 30(+)LymphocytepredominanceL&H (Popcorn cells)CD20 (+)CD 15(-),CD 30(-)
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now