After using transdermal nitroglycerin skin patches for 1 week, a patient with an 8-month history of chronic stable angina pectoris observes an increasing frequency of mild angina episodes during exeion. The patient has been conscientiously applying a new patch every morning immediately after removing the old one. The patient’s increased frequency of anginal attacks is most likely because of
After using transdermal nitroglycerin skin patches for 1 week, a patient with an 8-month history of chronic stable angina pectoris observes an increasing frequency of mild angina episodes during exeion. The patient has been conscientiously applying a new patch every morning immediately after removing the old one. The patient’s increased frequency of anginal attacks is most likely because of
💡 Explanation
After using transdermal nitroglycerin skin patches for 1 week, a patient with an 8-month history of chronic stable angina pectoris observes an increasing frequency of mild angina episodes during exeion. The patient has been conscientiously applying a new patch every morning immediately after removing the old one. The patient's increased frequency of anginal attacks is most likely because of
✓ Correct Answer: C. Cellular tolerance to organic nitrates
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