Reiter 's syndrome now referred to as reactive ahritis (ReA), is a classic triad of ahritis, nongonococcal urethritis and conjunctivitis. Reactive ahritis is triggered following enteric or urogenital infections. Reactive ahritis is associated with human leukocyte antigen (HLA)-B27. Bacteria associated with reactive ahritis are generally enteric or venereal. Reactive ahritis falls under the rheumatic disease category of seronegative spondyloahropathies, which includes ankylosing spondylitis, psoriatic ahritis, the ahropathy of associated inflammatory bowel disease, juvenile-onset ankylosing spondylitis, juvenile chronic ahritis, and undifferentiated spondyloahritis.