The most common cancer, affecting both male and females of the world, is –
**Core Concept**
The question is testing knowledge of the epidemiology of cancer, specifically the most common type of cancer that affects both men and women worldwide. This requires an understanding of global cancer statistics and the prevalence of various types of cancer.
**Why the Correct Answer is Right**
The correct answer is **Breast cancer**. Breast cancer is the most common cancer affecting women worldwide, accounting for approximately 11.7% of all new cancer cases in women. It is also a significant cause of cancer-related mortality in women. This is because breast cancer arises from the epithelial cells of the breast, which are susceptible to genetic mutations and environmental factors that can lead to cancer development.
**Why Each Wrong Option is Incorrect**
**Option A:** Lung cancer is a common cancer, but it is more prevalent in men than women, and its incidence varies greatly depending on geographic location and exposure to tobacco smoke.
**Option B:** Colorectal cancer is a significant cause of cancer-related mortality, but it is not the most common cancer affecting both men and women worldwide.
**Option C:** Prostate cancer is the most common cancer in men, but it is not the most common cancer affecting both men and women worldwide.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that breast cancer is the most common cancer affecting women worldwide, and its incidence is increasing in developing countries due to improved diagnostic techniques and increased awareness.
**Correct Answer:** D. Breast cancer.