**Core Concept**
Lignocaine (lidocaine) is a local anesthetic drug used for infiltration anesthesia, regional anesthesia, and other applications. The addition of adrenaline (epinephrine) to lignocaine can help prolong the duration of anesthesia, reduce toxicity, and provide vasoconstriction.
**Why the Correct Answer is Right**
The maximum dose of lignocaine with adrenaline is 7 mg/kg without any upper limit on adrenaline concentration. This is because adrenaline helps to slow the absorption of lignocaine into the bloodstream, reducing the risk of systemic toxicity. The maximum dose of lignocaine without adrenaline is 4.5 mg/kg, so the addition of adrenaline allows for a higher dose to be administered safely.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not provide a specific dose or context for comparison.
**Option B:** This option is incorrect because it is lower than the maximum dose allowed with adrenaline.
**Option C:** This option is incorrect because it is higher than the maximum dose allowed with adrenaline.
**Clinical Pearl / High-Yield Fact**
When administering local anesthetics, it is essential to consider the maximum safe dose and the addition of vasoconstrictors like adrenaline to minimize systemic toxicity.
**Correct Answer: B. 4.8 mg/kg**
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