ADAMTS 13 is associated with:
Correct Answer: TTP
Description: Ans. a. TTPThrombotic thrombocytopenic purpura (TTP) is a rare disorder of hemostasis in which there is widespread intravascular formation of fibrin-platelet thrombi.It is sometimes associated with an acquired or inherited deficiency of the enzyme ADAMTS 13, responsible for cleaving large multimers of von Willebrand factor.Clinically, TTP most often affects adult women.The inclusion criteria are microangiopathic hemolytic anemia and thrombocytopenia, with or without renal failure or neurologic abnormalities.Pathology includes widespread formation of platelet thrombi with fibrin (hyaline thrombi) leading to intravascular hemolysis (thrombotic microangiopathy).
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now