**Question:** Acute Primary Amoebic meningoencephalitis true is -

A. Acute bacterial meningitis
B. Acute viral meningitis
C. Acute fungal meningitis
D. Acute parasitic meningitis

**Correct Answer:** D. Acute parasitic meningitis

**Core Concept:**
Acute Primary Amoebic Meningoencephalitis (APAME) is a severe and potentially fatal disease caused by the protozoan parasite, Naegleria fowleri. This infection primarily affects the central nervous system (CNS) and can lead to rapid neurological deterioration if left untreated.

**Why the Correct Answer is Right:**
APAME is a rare but severe infection affecting the CNS, which is caused by the primary amoeba N. fowleri. This parasite enters the body through the nasal cavity, then migrates to the CNS, where it multiplies and causes inflammation and destruction of brain tissue. Among the given options, D. Acute parasitic meningitis is correct because APAME is a parasitic infection involving the meninges and brain parenchyma.

**Why Each Wrong Option is Incorrect:**

A. Acute bacterial meningitis: This option refers to infections caused by bacteria and is unrelated to APAME, which is a parasitic infection.

B. Acute viral meningitis: This option refers to infections caused by viruses and is not related to APAME, which is a parasitic infection.

C. Acute fungal meningitis: This option refers to infections caused by fungi and is not related to APAME, which is a parasitic infection.

**Clinical Pearl:**

N. fowleri infections are usually associated with exposure to contaminated water, particularly in warm and humid climates. Symptoms include fever, headache, seizures, coma, and rapidly progressive neurological deterioration. Early diagnosis and treatment with appropriate antileishmanial or antiprotozoal drugs are crucial for improving patient outcomes.

**Why Each Wrong Option is Incorrect:**

A. Acute bacterial meningitis: This option is incorrect because APAME is caused by a protozoan parasite, not bacteria.

B. Acute viral meningitis: This option is incorrect because APAME is caused by a protozoan parasite, not a virus.

C. Acute fungal meningitis: This option is incorrect because APAME is caused by a protozoan parasite, not a fungus.