Activation of the following type of receptors present on myenteric neurons by metoclopramide is primarily responsible for the enhanced acetylcholine release and improving gastric motility:
Correct Answer: Serotonergic 5-HT4
Description: (Ref: KDT 6/e p646, 647) Gastric motility is increased by ACh. Release of this neurotransmitter is enhanced by 5HT4 receptor stimulation and 5HT3 and D2 receptor antagonism.
Category:
Pharmacology
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